Surnames beginning with S
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- Santilukka
- Santimano
- Santimateo Brias
- Santimaw
- Santimays
- Santimen
- Santin
- Santina
- Santine
- Santineer
- Santinella
- Santinelli
- Santinello
- Santing
- Santinho
- Santini
- Santini Jr
- Santino
- Santinon
- Santinor
- Santio
- Santiquian
- Santis
- Santisi
- Santiso
- Santisteban
- Santisteban Bolivar
- Santistevan
- Santivanez
- Santizas
- Santizo
- Santjer
- Santkiewicz
- Santlard
- Santle
- Santler
- Santles
- Santlewood
- Santley
- Santley Dilley
- Santly
- Santman
- Santmier
- Santmire
- Santmyer
- Santner
- Sant-Noell
- Santo
- Santo Amaro
- Santocchi
- Santocchini
- Santochirico
- Santockis
- Santocono
- Santodomingo
- Santo Domingo
- Santo Domingo Davila
- Santoianni
- Santojanni
- Santoja Sanchez
- Santoki
- Santokie
- Santolaria
- Santolaya
- Santoleri
- Santolero
- Santoli
- Santolin
- Santolini
- Santoliquido
- Santolla
- Santolorin
- Santolucito
- Santom
- Santomarco
- Santomassimo
- Santomauro
- Santon
- Santona Frazier
- Santonastaso
- Santone
- Santoni
- Santonna
- Santonocito
- Santopadre
- Santopaolo
- Santopietro
- Santopolo
- Santor
- Santora
- Santore
- Santorella
- Santorelli
- Santorelli-Bates
- Santori
- Santoriella
- Santoriello
- Santoriello-Smith
- Santorini
- Santorio
Surnames shown in bold text represent around 90% of the population of Great Britain. All other names are very uncommon in the UK and we are unlikely to have any useful data on them.